Featured image of the article Hansoh Pharma and Roche forge global alliance to advance CDH17-targeting ADCs for solid tumors.

Hansoh Pharma and Roche forge global alliance to advance CDH17-targeting ADCs for solid tumors

SOPHIA ANTIPOLIS, France – October 24, 2025 │ Hansoh Pharmaceutical has signed a license agreement with Roche to develop HS-20110, a CDH17-targeting antibody-drug conjugate (ADC) utilizing a clinically validated topoisomerase inhibitor payload. Hansoh Pharma gives Roche an exclusive worldwide license (excluding the Chinese Mainland, Hong Kong, Macau and Taiwan) to advance the clinical development and[…]

Featured image of the article Clinical Evolution and Regulatory Success of Regeneron’s BCMA×CD3 bsAb Linvoseltamab.

Clinical Evolution and Regulatory Success of Regeneron’s BCMA×CD3 bsAb Linvoseltamab

SOPHIA ANTIPOLIS, France – July 10, 2025 │ In July, Regeneron received accelerated approval from the FDA for its bispecific antibody (bsAb) Linvoseltamab (brand name Lynozyfic). It is intended to treat adult patients with relapsed or refractory (R/R) multiple myeloma (MM) who have received at least 4 prior lines of therapy, including a proteasome inhibitor,[…]

Featured image of the article CytomX’s CX-2051: unlocking EpCAM with Probody® ADCs in advanced colorectal cancer.

CytomX’s CX-2051: unlocking EpCAM with Probody® ADCs in advanced colorectal cancer

SOPHIA ANTIPOLIS, France – May 30, 2025 │ CytomX Therapeutics announced positive Phase 1 data for its Epithelial Cell Adhesion Molecule (EpCAM) PROBODY® Antibody Drug Conjugate candidate, CX-2051, in advanced Colorectal Cancer (CRC). CytomX Therapeutics: precision oncology through Probody® innovation CytomX Therapeutics is based in South San Francisco, California. It was founded in 2008 by[…]

Featured image of the article Unlocking new cancer targets: Oxford BioTherapeutics and Roche leverage OGAP®-Verify in strategic collaboration.

Unlocking new cancer targets: Oxford BioTherapeutics and Roche leverage OGAP®-Verify in strategic collaboration

SOPHIA ANTIPOLIS, France – April 11th, 2025 │ On March 19th, 2025, a collaboration was announced between Oxford BioTherapeutics (OBT) and Roche to discover novel potentially first-in-class antibody-based therapeutics for the treatment of cancer. Targets will be identified via the OGAP®-Verify discovery platform of OBT, a proprietary database on membrane protein abundance, with around 7,000[…]